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The hydrochloride salt form of mepivacaine, an amide-type local anesthetic agent. At the injection site, mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand names:||Carbocaine |
|Chemical structure:||1-methyl-2',6'-pipecoloxylidide hydrochloride (SY), (1-methyl-DL-piperidine-2-carboxylic acid)-2,6-dimethylanilide hydrochloride|