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A synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)