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NCI Drug Dictionary

NCI Drug Dictionary

  

azaserine 
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:diazoacetate (ester) L-Serine
diazoacetic acid ester with serine
diazoacetylserine
serine diazoacetate
Abbreviations:AZAS
AZS
Code names:CL-337
CN-15757
P-165
Chemical structures:L-diazoacetate (ester) serine
L-serine diazoacetate (ester)
O-diazoacetyl-L-serine
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