NCI Drug Dictionary
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A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||diazoacetate (ester) L-Serine |
diazoacetic acid ester with serine
|Code names:||CL-337 |
|Chemical structures:||L-diazoacetate (ester) serine |
L-serine diazoacetate (ester)