NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- golnerminogene pradenovec
A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: adenovirus 5-tumor necrosis factor alpha
tumor necrosis factor adenovirus 5 vector
US brand name: TNFerade Abbreviations: Ad 5-TNF Alpha
Code name: ADgv EGR.TNF.11D