NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A human monoclonal antibody produced in transgenic mice that attaches to the transmembrane epidermal growth factor (EGF) receptor. Panitumumab may inhibit autocrine EGF stimulation of tumor cells that express the EGF receptor, thereby inhibiting tumor cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: clone E7.6.3
monoclonal antibody ABX-EGF
US brand name: Vectibix Abbreviation: MOAB ABX-EGF Code name: ABX-EGF