NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

apolizumab
A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:1D1O Anti-lymphoma Antibody
Monoclonal antibody 1D10
Monoclonal Antibody Hu1D10
US brand name:Remitogen
Abbreviations:MOAB 1D10
MoAb Hu1D10