NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name: Aldara Abbreviation: IMQ Code names: R 837
Chemical structures: 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-