NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

inalimarev
A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1 (mucin-1), a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of the three co-stimulatory molecule transgenes B7-1, ICAM-1 and LFA-3. Upon administration, inalimarev may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and may activate a cytotoxic T lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:recombinant vaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
recombinant vaccinia-CEA-MUC1-TRICOM vaccine
rVaccinia-CEA(D609)/MUC1(L93)/TRICOM vaccine
vaccinia-CEA-MUC-1-TRICOM vaccine
US brand name:PANVAC-V
Abbreviation:vCEA-MUC-1-TRI