NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

decitabine
Patient Information A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:5-aza-dCyd
deoxyazacytidine
dezocitidine
US brand name:Dacogen
Abbreviations:5AZA
DAC
Chemical structures:2'-deoxy-5-azacytidine
4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
5-aza-2'-deoxycytidine
5-aza-2-deoxycytidine
5-azadeoxycytidine