NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

etanidazole
A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may also be useful as an imaging agent for identifying hypoxic, drug-resistant regions of primary tumors or metastases. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym:2-nitro-imidazole derivative
Code name:SR-2508
Chemical structures:1H-imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-
2-nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-