NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
An iodinated analogue of deoxyuridine. Idoxuridine incorporates into DNA during the S-phase of the cell cycle, sensitizing cells to ionizing radiation by increasing DNA strand breaks. When this agent contains a radioactive isomer of iodine, the radioactive idoxuridine kills cancer cells directly after preferential incorporation into the DNA of rapidly dividing tumor cells. Check for active clinical trials using this agent. (NCI Thesaurus)
US brand names: Dendrid
Foreign brand names: Idexur
Abbreviation: IUDR Code name: SKF 14287 Chemical structures: 1-(2-deoxy-beta-D-ribofuranosyl)-5-iodouracil