NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

methylmercaptopurine riboside
A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym:methylthioinosine
Abbreviations:6-MMPR
MMPR
Code names:NCI-C04784
SQ 21977
Chemical structures:6-(methylmercapto)purine ribonucleoside
6-(methylthio) inosine
6-(methylthio)purine ribonucleoside
6-(methylthio)purine riboside
6-methyl MP riboside
6-methylmercaptopurine riboside
6-methylthioinosine
9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl
9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI)
9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate
beta-D-ribosyl-6-methylthiopurine
purine-6-thiol,6-methyl-9-ribofuranosyl