NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

lidocaine
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. Check for active clinical trials using this agent. (NCI Thesaurus)
US brand names:Lidothesin
Xylocaine
Xylocitin
Foreign brand names:Cuivasil
Duncaine
Leostesin
Lignocaine
Rucaina
Xylotox
Chemical structures:2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-diethylamino-2',6'-acetoxylidide
omega-diethylamino-2,6-dimethylacetanilide