NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: mercaptoethane sulfonate
US brand name: Mesnex Foreign brand names: Ausobronc
Abbreviation: MSA Code names: D-7093
Chemical structures: 2-mercaptoethanesulfonic acid, sodium salt
sodium 2-mercaptoethane sulfonate