NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

dacarbazine
Patient Information A triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:Biocarbazine
Dacarbazina
Dacarbazina Almirall
Dacarbazine - DTIC
Dakarbazin
Dimethyl (triazeno) imidazolecarboxamide
Dimethyl Triazeno Imidazol Carboxamide
Dimethyl Triazeno Imidazole Carboxamide
Imidazole Carboxamide
Imidazole Carboxamide Dimethyltriazeno
US brand name:DTIC-Dome
Foreign brand names:Asercit
Dacatic
Deticene
Detimedac
Fauldetic
Abbreviations:DIC
DTIC
Code name:WR-139007
Chemical structures:1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
5-(3-3-dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
5-(dimethyltriazeno)imidazole-4-carboxamide
5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide