NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF) isoform B, with immunomodulating activity. Filgrastim binds to and activates G-CSF receptors with the same biological activity and stability as the endogenous cytokine, thereby controlling the production, differentiation, and function of neutrophilic granulocyte progenitors. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: filgrastim XM02
granulocyte colony-stimulating factor
Recombinant Methionyl Human Granulocyte Colony Stimulating Factor
US brand names: Neupogen
Foreign brand name: Nivestim Abbreviations: G-CSF