NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

ormaplatin
A platinum(IV) analogue with antineoplastic activity. Ormaplatin alkylates DNA, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonym:tetraplatin
Chemical structure:tetrachloro(1,2-cyclohexanediamine-N,N')-, (OC-6-22-(trans))platinum