NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

recombinant human stem cell factor
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:c-kit ligand
mast-cell growth factor
recombinant methionyl human stem cell factor
r-metHuSCF
steel factor
US brand name:Ancestim
Acronym:rhSCF