NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

daclizumab
A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2 (IL-2) receptor expressed on the surface of activated lymphocytes in vivo, thereby inhibiting IL-2 binding and IL-2-mediated lymphocyte activation, a critical cellular immune response pathway. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:anti-Tac
Anti-Tac Humanized Monoclonal Antibody
anti-Tac monoclonal antibody
Dacliximab
US brand name:Zenapax
Abbreviation:MOAB anti-Tac