NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

niacinamide
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:3-Pyridinecarboxamide
nicotinamide
Nicotinamidum
Nicotinic Acid Amide
Nicotylamide
Pellagra-Preventing Factor
Vitamin PP
Foreign brand names:Nicamid
Nicosedine