NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

disaccharide tripeptide glycerol dipalmitoyl
A lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity. Disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP)stimulates macrophage activity and increases serum levels of tumor necrosis factor alpha (TNF alpha), neopterin, interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8, and IL-12, which may activate host immune system antitumor functions. DTP-GDP may be packaged in liposomes for improved delivery. The immunomodulatory effects of this agent may be superior to those of MDP. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:ImmTher
Abbreviation:DTP-GDP
Chemical structure:N-acetylglucosaminyl-N-acetyhnuramyl-L-Ala-isoGlu-L-Ala-glycerol dipalmitate