NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

epratuzumab
A recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:AMG 412
Humanized Anti-CD22 Monoclonal Antibody IgG1
LL2
monoclonal antibody LL2
US brand name:LymphoCide
Abbreviations:hLL2
MOAB LL2