NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

samarium Sm 153 lexidronam pentasodium
The pentasodium salt of samarium Sm 153 lexidronam, a therapeutic agent consisting of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 153, and a teraphosphonate chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated cytotoxic radiation to osteoblastic bone metastases. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:samarium Sm 153 lexidronam
Samarium-153 EDTMP
Sm 153 lexidronam pentasodium
US brand name:Quadramet
Abbreviations:153Sm-EDTMP
Sm-153 EDTMP