NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

motexafin gadolinium
A synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:gadolinium texaphyrin
Gd (III) Texaphryin
US brand name:Xcytrin
Abbreviation:Gd-Tex
Code name:PCI-0120