NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

Patient Information A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:BI 695500
C2B8 Monoclonal Antibody
IDEC-C2B8 monoclonal antibody
rituximab biosimilar PF-05280586
rituximab biosimilar RTXM83
US brand name:Rituxan
Foreign brand name:Mabthera
Abbreviation:MOAB IDEC-C2B8
Code names:IDEC-102