NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

diethylstilbestrol
DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:diethylstilbestrol dipropionate
diethylstilbestrolum
Sinestrol
stilboestrol dipropionate
US brand names:Acnestrol
Cyren A
Deladumone
Diastyl
Domestrol
Estrobene
Estrosyn
Fonatol
Makarol
Milestrol
Neo-Oestronol I
Oestrogenine
Oestromenin
Oestromon
Palestrol
Stilbestrol
Stilbetin
Stilboestroform
Stilboestrol
Synestrin
Synthoestrin
Vagestrol
Foreign brand names:Antigestil
Apstil
Boestrol
Bufon
Distilbene
Estrogenine
Estromenin
Grafestrol
Microest
Oestromensyl
Serral
Sexocretin
Sibol
Stilboefral
Stilkap
Abbreviation:DES
Chemical structures:(E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol
3,4-bis(p-hydroxyphenyl)-3-hexene
4,4'-dihydroxy-alpha,beta-diethylstilbene
alpha,alpha'-diethylstilbenediol
trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3