NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

batabulin sodium
A synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. Batabulin sodium covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton, an increase in chromosomal ploidy, cell cycle arrest, and tumor cell apoptosis. Check for active clinical trials using this agent. (NCI Thesaurus)
Code name:T138067
Chemical structures:2-fluoro-1-methoxy-4-(pentafluorophenyl-sulfonamido)benzene, sodium salt
2-fluoro-1-methoxy-4-pentafluorophenylsulfonamidobenzene