NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- p53 peptide vaccine
A peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53 gene. p53 peptide vaccine may elicit an HLA-A2.1-restricted cytotoxic T lymphocyte immune response against tumor cells that overexpress p53 protein. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: individualized mutant p53 peptide-pulsed cultured autologous dendritic cell vaccine
P53 (264-272) peptide vaccine and tumor-specific mutant p53 peptide vaccine
Abbreviation: p53 VAC