NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

p53 peptide vaccine
A peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53 gene. p53 peptide vaccine may elicit an HLA-A2.1-restricted cytotoxic T lymphocyte immune response against tumor cells that overexpress p53 protein. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:individualized mutant p53 peptide-pulsed cultured autologous dendritic cell vaccine
P53 (264-272) peptide vaccine and tumor-specific mutant p53 peptide vaccine
Abbreviation:p53 VAC