NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

picoplatin
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code names:AMD473
NX 473
ZD0473
Chemical structures:Cis-Amminedichloro (2-Methylpyridine) Platinum
Platinum, Amminedichloro(2-methylpyridine)-, (SP-4-3)