NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- atomoxetine hydrochloride
The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft; the effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels. Check for active clinical trials using this agent. (NCI Thesaurus)
US brand name: Strattera Chemical structure:
- (-)-N -methyl-3-phenyl-3-(o-tolyloxy)-propylamine hydrochloride
- (-)-N-methyl-gamma(2-methylphenoxy)benzenepropamine Hydrochloride