NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine
- A cancer vaccine containing multiple synthetic antigen peptides derived from MAGE-A1, Her-2/neu, and folate binding protein (FBP) with potential immunostimulating and antineoplastic properties. MAGE-A1, Her-2/neu, FBP peptides cancer vaccine includes the antigen peptides MAGE-A1:161-169, FBP:191-199, Her-2/neu:369-377, MAGE-A1:96-104, and Her-2/neu:754-762. Upon administration, this cancer vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing these antigen peptides, resulting in tumor cell lysis. MAGE-A1, Her-2/neu, and FBP proteins may be over-expressed in various cancer cell types, such as epithelial ovarian cancer cells. Check for active clinical trials using this agent. (NCI Thesaurus)