NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

povidone-iodine solution
An iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the povoiodine-iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytosplasmic and membrane compounds. This agent exhbits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:Betadine topical
iodine povidone topical
iodopovidone solution
US brand names:Betadine
Betadine Solution
E-Z Prep
E-Z Scrub
Abbreviation:PVP iodine