NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

tazarotene
A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand names:Avage
Tazorac
Foreign brand names:Retisol-A
Stieva-A
Stieva-A Forte
Vitinoin
Code name:AGN-190168
Chemical structures:6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-Pyridinecarboxylic Acid, Ethyl Ester
Ethyl 6-(2-(4,4-Dimethylthiochroman-6-yl)ethynyl)nicotinate