NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

allogeneic GM-CSF-transfected myeloma cell vaccine
An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon vaccination, allogeneic GM-CSF-based myeloma cellular vaccine secretes GM-CSF, which may potentiate a tumor-specific cytotoxic T-lymphocyte (CTL) response against myeloma cancer cell-associated antigens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:allogeneic GM-CSF-based myeloma cell vaccine
allogeneic granulocyte macrophage colony-stimulating factor-transfected myeloma cell vaccine