NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- fluciclatide F 18
A radiopharmaceutical compound of a small synthetic cyclic peptide containing an RGD-sequence (Arg-Gly-Asp) labeled with the positron-emitting isotope fluorine F 18 that may be used to selectively image tumor cells and tumor vasculature by PET imaging. The RGD motif of fluciclatide F 18 selectively binds to the alphaVbeta3 integrin receptor, commonly upregulated on the surfaces of tumor cells and endothelial cells of tumor vasculature. This agent may be of use in visualizing and quantifying the development of tumor vascularity in response to antiangiogenic agents. Check for active clinical trials using this agent. (NCI Thesaurus)
- 6-N-[(28E)-29-(4-[18F]fluorophenyl)-5,25-dioxo-3,9,12,15,18,21,27-heptaoxa-6,24,28- triazanonacos-28-enoyl]-2-N-(2-sulfanylacetyl)-L-lysyl-L-cysteinyl-L-arginylglycyl-L-α- aspartyl-L-cysteinyl-L-phenylalanyl-1-N-(17-amino-13,17-dioxo-3,6,9,15-tetraoxa-12- azaheptadecyl)-L-cysteinamide cyclic (2→6)-disulfide cyclic (1→8)-thioether
- L-cysteinamide, N6-[29-[4-(fluoro-18F)phenyl]-1,5,25-trioxo-3,9,12,15,18,21,27- heptaoxa-6,24,28-triazanonacos-28-en-1-yl]-N2-(2-mercaptoacetyl)-L-lysyl-L-cysteinyl- L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-N-(17-amino-13,17-dioxo- 3,6,9,15-tetraoxa-12-azaheptadec-1-yl)-, cyclic (1→8)-thioether, cyclic (2→6)-disulfide