NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

oxymorphone hydrochloride
The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression. Check for active clinical trials using this agent. (NCI Thesaurus)
US brand names:Numorphan
Opana
Chemical structure:4,5-alpha-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one hydrochloride