NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. Check for active clinical trials or closed clinical trials using this agent.
Synonyms: anti-IgE monoclonal antibody E25
US brand name: Xolair Abbreviation: rhuMAb-E25 Code name: IGE 025