NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

liposome-encapsulated recombinant human enzyme Cu/Zn superoxide-dismutase
A topical hydrophilic gel containing a recombinant form of the human Cu/Zn superoxide dismutase (SOD1), a cytoplasmic antioxidant enzyme, encapsulated in liposomes with potential anti-inflammatory and adjuvant activities. Upon application of liposome-encapsulated recombinant human Cu/Zn SOD as a thin film on the irradiated area, the recombinant SOD1 is released and scavenges free oxygen radicals, thereby protecting cells from oxidative stress. This may prevent radiation-induced dermatitis as well as other types of skin reactions. Check for active clinical trials using this agent.
Synonym:liposome-encapsulated recombinant human enzyme Cu/Zn SOD
Foreign brand name:Lipoxysan
Code name:APN201