NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

long-acting granulocyte colony-stimulating factor receptor SPI-2012
A long-acting, recombinant analog of the endogenous human granulocyte colony-stimulating factor (G-CSF) with hematopoietic activity. Similar to G-CSF, long-acting G-CSF analog SPI-2012 binds to and activates specific cell surface receptors and stimulates neutrophil progenitor proliferation and differentiation, as well as selected neutrophil functions. Therefore, this agent may decrease the duration and incidence of chemotherapy-induced neutropenia. The long-acting G-CSF analog SPI-2012 extends the half-life of G-CSF, allowing for administration once every 3 weeks. Check for active clinical trials using this agent. (NCI Thesaurus)
Abbreviation:LAPS-GCSF
Code names:HM10460A
SPI-2012