NCI Drug Dictionary
The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.
- carbon C 13 acetate
The non-radioactive, naturally occurring isotope of acetate, carbon C 13 acetate, with potential use for metabolic tumor imaging upon nuclear magnetic resonance (NMR) spectroscopy. Upon infusion, carbon C 13 acetate is taken up by cancer cells and is utilized by metabolic pathways in the tumor cell. Specifically, the tumor cells oxidize acetate, in the form of acetyl coenzyme A (acetyl-CoA), in the citric acid cycle. Upon 13C-NMR, the metabolic phenotype of a tumor can be assessed. Certain alternative metabolic pathways are activated in tumor cells and use substrates other than glucose, such as acetate, for acetyl-CoA production. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms: 1,2-13C acetate