NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,811 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

CC49-streptavidin
(… strep-TA-vih-din)
A substance that is being studied in the treatment of cancer. It is made by combining the monoclonal antibody CC49 with a chemical called streptavidin. It can find tumor cells that have the protein TAG-72 on their surface, including colon, prostate, breast, and ovary cancer cells. After CC49-streptavidin binds to cancer cells, a radioactive compound called yttrium Y 90 DOTA-biotin will find those cells and kill them.