NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,879 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

5-FU
A drug used to treat cancers of the breast, colon, rectum, stomach, and pancreas. Under the brand names Carac, Tolak, Efudex, and Fluoroplex, it is used as a cream to treat actinic keratosis (a skin condition that may become cancer). It is also used under the brand name Efudex as a cream to treat basal cell skin cancer that is superficial (not invasive) and cannot be removed by surgery. 5-FU is being studied in the treatment of other conditions and types of cancer. It stops cells from making DNA and may kill cancer cells. 5-FU is a type of antimetabolite. Also called 5-fluorouracil, Carac, Efudex, Fluoroplex, fluorouracil, and Tolak.