NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,777 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

stage IV prostate cancer
(...PROS-tayt KAN-ser)
Cancer (1) has spread beyond the seminal vesicles to nearby tissue or organs, such as the rectum, bladder, or pelvic wall; or (2) has spread to nearby lymph nodes and may have spread to the seminal vesicles or to nearby tissue or organs, such as the rectum, bladder, or pelvic wall; or (3) has spread to distant parts of the body, which may include lymph nodes or bones. Also, the prostate-specific antigen (PSA) can be any level and the Gleason score can range from 2 to 10.

EnlargeProstate cancer staging; six  panel drawing showing a side view of normal  male  anatomy and closeup views of Stage I, Stage IIA, Stage IIB, Stage III, and Stage IV  showing cancer growing from within the  prostate to nearby tissue and then to lymph nodes or other parts of the body.

As prostate cancer progresses from Stage I to Stage IV, the cancer cells grow within the prostate, through the outer layer of the prostate into nearby tissue, and then to lymph nodes or other parts of the body.