NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,790 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

peripheral blood stem cell transplant
(peh-RIH-feh-rul ... stem sel TRANZ-plant)
A method of replacing blood-forming cells destroyed by cancer treatment. Immature blood cells (stem cells) in the bloodstream are given to the patient after treatment. This helps the bone marrow recover and continue to make healthy blood cells. A stem cell transplant may be autologous (a patient’s own blood cells saved earlier), allogeneic (blood cells donated by someone else), or syngeneic (blood cells donated by an identical twin). Also called peripheral stem cell support.

EnlargeDrawing of stem cells being removed from a patient or donor. Blood is collected from a vein in the arm and flows through a machine that removes the stem cells; the remaining blood is returned to a vein in the other arm.

Stem cell transplant (Step 1). Blood is taken from a vein in the arm of the donor. The patient or another person may be the donor. The blood flows through a machine that removes the stem cells. Then the blood is returned to the donor through a vein in the other arm.

EnlargeDrawing of a health care provider giving a patient treatment to kill blood-forming cells. Chemotherapy is given to the patient through a catheter in the chest.

Stem cell transplant (Step 2). The patient receives chemotherapy to kill blood-forming cells. The patient may receive radiation therapy (not shown).

EnlargeDrawing of stem cells being given to the patient through a catheter in the chest.

Stem cell transplant (Step 3). The patient receives stem cells through a catheter placed into a blood vessel in the chest.