NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 7,881 terms related to cancer and medicine.
Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.
- phase I clinical trial
- listen (fayz … KLIH-nih-kul TRY-ul)
- The first step in testing a new treatment in humans. A phase I study tests the safety, side effects, best dose, and timing of a new treatment. It may also test the best way to give a new treatment (for example, by mouth, infusion into a vein, or injection) and how the treatment affects the body. The dose is usually increased a little at a time in order to find the highest dose that does not cause harmful side effects. Phase I clinical trials usually include only a small number of patients who have not been helped by other treatments. Sometimes they include healthy volunteers.