NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,800 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

ondansetron hydrochloride
(on-DAN-seh-tron HY-droh-KLOR-ide)
A drug used to prevent nausea and vomiting caused by chemotherapy and radiation therapy. It is also used to prevent nausea and vomiting after surgery. Ondansetron hydrochloride blocks the action of the chemical serotonin, which binds to certain nerves and may trigger nausea and vomiting. Blocking serotonin may help lessen nausea and vomiting. It is a type of serotonin receptor antagonist and a type of antiemetic. Also called Zofran.