NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,780 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

BCR-ABL fusion protein
(... FYOO-zhun PROH-teen)
A protein made from pieces of two genes that get joined together. It is found in most patients with chronic myelogenous leukemia (CML), and in some patients with acute lymphoblastic leukemia (ALL) or acute myelogenous leukemia (AML). Inside the leukemia cells, the ABL gene from chromosome 9 joins to the BCR gene on chromosome 22 to form the BCR-ABL fusion gene, which makes the BCR-ABL fusion protein.