NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,804 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

liver X receptor alpha pathway
(LIH-ver … reh-SEP-ter AL-fuh PATH-way)
Describes a group of proteins in a cell that work together to help control how certain genes are expressed and how cholesterol, lipids (fats), bile acids, and steroid hormones are made in the body. Changes in the liver X receptor alpha pathway may lead to diseases such as heart disease and cancer. Drugs or substances that affect this pathway are being studied in the prevention and treatment of cancer and other diseases. Also called LXR alpha pathway.