NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,791 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

glucose-6-phosphate dehydrogenase deficiency
(GLOO-kose-6-FOS-fayt dee-hy-DRAH-jeh-nays deh-FIH-shun-see)
An inherited disorder in which a person doesn’t have enough of an enzyme called G6PD that helps red blood cells work the way they should. In glucose-6-phosphate dehydrogenase deficiency, the red blood cells break down when the body is exposed to infection, severe stress, or certain drugs, chemicals, or foods. This may lead to a condition called hemolytic anemia. This disorder is most common in African-American men and in men of Middle Eastern or Mediterranean descent. Also called G6PD deficiency.