NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,812 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

24 results found for: Y
Y 90 ibritumomab tiuxetan
(... ih-brih-TOO-moh-mab ty-UK-seh-tan)
A drug used with the drug rituximab to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of B-cell tumors. Y 90 ibritumomab tiuxetan contains a monoclonal antibody that binds to a protein called CD20, which is found on B cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Y 90 ibritumomab tiuxetan is a type of radioimmunoconjugate. Also called IDEC-Y2B8, Y 90 Zevalin, and yttrium Y 90 ibritumomab tiuxetan.
Y 90 Zevalin
(... ZEH-vuh-lin)
A drug used with the drug rituximab to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of B-cell tumors. Y 90 Zevalin contains a monoclonal antibody that binds to a protein called CD20, which is found on B cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Y 90 Zevalin is a type of radioimmunoconjugate. Also called IDEC-Y2B8, Y 90 ibritumomab tiuxetan, and yttrium Y 90 ibritumomab tiuxetan.
yangona
(yan-GOH-nuh)
An herb native to islands in the South Pacific. Substances taken from the root have been used in some cultures to relieve stress, anxiety, tension, sleeplessness, and problems of menopause. Yangona may increase the effect of alcohol and of certain drugs used to treat anxiety and depression. The U.S. Food and Drug Administration advises users that yangona may cause severe liver damage. The scientific name is Piper methysticum. Also called intoxicating pepper, kava kava, rauschpfeffer, and tonga.
yeast
(yeest)
A type of microorganism that is found almost everywhere, including inside the body. There are many different types of yeast. Some types are used to make foods, such as bread, cheese, and alcoholic drinks. Small amounts of a certain type of yeast normally live on the skin and in some parts of the body, such as the mouth, throat, and vagina. Yeast are a type of fungus.
yeast infection
(yeest in-FEK-shun)
A condition in which too much yeast grows in certain areas of the body and causes symptoms and disease. Small amounts of yeast normally live on the skin and in other parts of the body, such as the mouth, throat, and vagina. Sometimes, too much yeast can grow in these areas and cause infection. Yeast infections may also occur in the blood and spread throughout the body, but this is rare. Certain conditions, such as a weakened immune system, diabetes, pregnancy, hormone changes, and stress, and use of certain medicines may increase the risk of yeast infection.
yellow fever
(YEH-loh FEE-ver)
A disease caused by infection with the yellow fever virus, which is carried by mosquitos. Symptoms include body aches, chills, fever, severe headache, weakness, and a yellow skin color. Bleeding, vomiting, and failure of the liver and other organs may occur in late stages of the disease.
Yervoy
(YER-voy)
A drug used to treat melanoma that has spread to other parts of the body or that cannot be removed by surgery. It is also being studied in the treatment of other types of cancer. Yervoy binds to a substance called CTLA-4, which is found on the surface of T cells (a type of white blood cell). Yervoy may block CTLA-4 and help the immune system kill cancer cells. It is a type of monoclonal antibody. Also called ipilimumab and MDX-010.
yin and yang
(yin ... yang)
In Chinese philosophy, yin and yang are opposite forces that form a whole. Everything contains both yin and yang in a balance that is always changing, such as hot and cold, day and night, and health and disease. In traditional Chinese medicine, disease is diagnosed and treated based on the balance of yin and yang.
YKL-40
A substance that may be found in higher-than-normal amounts in the blood of patients with certain types of cancer and inflammatory diseases. It is a type of glycoprotein.
YM598
A substance that is being studied as a treatment for advanced prostate cancer and for pain caused by prostate cancer that has spread to the bone. It belongs to the family of drugs called endothelin ETA receptor antagonists.
yoga
(YOH-guh)
An ancient system of practices used to balance the mind and body through exercise, meditation (focusing thoughts), and control of breathing and emotions. Yoga is being studied as a way to relieve stress and treat sleep problems in cancer patients.
yohimbe
(yoh-HIM-bay)
A tree native to West Africa. The bark is used as a supplement for bodybuilding and to enhance male sexual performance. It contains the chemical yohimbine, which is being studied in the treatment of sexual dysfunction. It may interact with certain drugs used to treat depression, high blood pressure, and high blood sugar. The scientific name is Pausinystalia yohimbe. Also called johimbe.
yttrium
(IH-tree-um)
A metal of the rare earth group of elements. A radioactive form of yttrium may be attached to a monoclonal antibody or other molecule that can locate and bind to cancer cells and be used to diagnose or treat some types of cancer.
yttrium Y 90
(IH-tree-um …)
A radioactive form of the rare metal yttrium that is used in radiation therapy to treat some types of tumors. Yttrium Y 90 can be linked to a molecule, such as a monoclonal antibody, to help it locate and bind to certain substances in the body, including cancer cells. The radiation may kill the cancer cells.
yttrium Y 90 clivatuzumab tetraxetan
(IH-tree-um … KLY-vuh-TOO-zoo-mab teh-TRAK-seh-tan)
A substance being studied in the treatment of advanced pancreatic cancer. Yttrium Y 90 clivatuzumab tetraxetan contains a monoclonal antibody that binds to a protein called MUC-1, which is found on some pancreatic cancer cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 clivatuzumab tetraxetan is a type of radioimmunoconjugate. Also called yttrium Y 90 DOTA monoclonal antibody HuPAM4.
yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A
(IH-tree-um … MAH-noh-KLOH-nul AN-tee-BAH-dee …)
A substance being studied in the treatment of some types of cancer. M5A is a monoclonal antibody that binds to a protein called CEA on the surface of some tumor cells. It is linked to a radioisotope called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A is a type of radioimmunoconjugate and a type of radiopharmaceutical.
yttrium Y 90 DOTA monoclonal antibody HuAFP31
(IH-tree-um … MAH-noh-KLOH-nul AN-tee-BAH-dee …)
A substance being studied in the treatment of liver cancer. HuAFP31 is a monoclonal antibody that can bind to tumor cells that make a protein called alpha fetoprotein (AFP). It is linked to a radioactive substance called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuAFP31 is a type of radioimmunoconjugate.
yttrium Y 90 DOTA monoclonal antibody HuPAM4
(IH-tree-um ... MAH-noh-KLOH-nul AN-tee-BAH-dee ...)
A substance being studied in the treatment of advanced pancreatic cancer. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 contains a monoclonal antibody that binds to a protein called MUC-1, which is found on some pancreatic cancer cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 is a type of radioimmunoconjugate. Also called yttrium Y 90 clivatuzumab tetraxetan.
yttrium Y 90 DOTA-biotin
(IH-tree-um ... BY-oh-tin)
A compound that contains the radioisotope yttrium Y 90 linked to the chemical biotin. Biotin is a molecule that binds strongly to the chemical streptavidin. Yttrium Y 90 DOTA-biotin will find tumor cells in the body that have been targeted by an antibody linked to streptavidin and kill them. It is being studied together with CC49-streptavidin in the treatment of cancer. Also called 90Y-DOTA-biotin.
yttrium Y 90 DOTA-tyr3-octreotide
(IH-tree-um ... ok-TREE-oh-tide)
A substance being studied in the treatment of some types of cancer. Yttrium Y 90 DOTA-tyr3-octreotide contains a molecule that binds to a protein found on certain types of neuroendocrine tumors (tumors that form from cells that release hormones). It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 DOTA-tyr3-octreotide is a type of radioconjugate. Also called yttrium Y 90 edotreotide and yttrium Y 90 SMT 487.
yttrium Y 90 edotreotide
(IH-tree-um ... eh-doh-TREE-oh-tide)
A substance being studied in the treatment of some types of cancer. Yttrium Y 90 edotreotide contains a molecule that binds to a protein found on certain types of neuroendocrine tumors (tumors that form from cells that release hormones). It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 edotreotide is a type of radioconjugate. Also called yttrium Y 90 DOTA-tyr3-octreotide and yttrium Y 90 SMT 487.
yttrium Y 90 epratuzumab tetraxetan
(IH-tree-um … eh-pruh-TOO-zoo-mab teh-TRAK-seh-tan)
A substance being studied in the treatment of certain types of B-cell cancer. Epratuzumab is a monoclonal antibody that binds to a protein called CD22, which is found on the surface of B cells. It is linked to a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 epratuzumab tetraxetan is a type of radioimmunoconjugate.
yttrium Y 90 ibritumomab tiuxetan
(IH-tree-um ... ih-brih-TOO-moh-mab ty-UK-seh-tan)
A drug used with the drug rituximab to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of B-cell tumors. Yttrium Y 90 ibritumomab tiuxetan contains a monoclonal antibody that binds to a protein called CD20, which is found on B cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 ibritumomab tiuxetan is a type of radioimmunoconjugate. Also called IDEC-Y2B8, Y 90 ibritumomab tiuxetan, and Y 90 Zevalin.
yttrium Y 90 SMT 487
(IH-tree-um …)
A substance being studied in the treatment of some types of cancer. Yttrium Y 90 SMT 487 contains a molecule that binds to a protein found on certain types of neuroendocrine tumors (tumors that form from cells that release hormones). It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 SMT 487 is a type of radioconjugate. Also called yttrium Y 90 DOTA-tyr3-octreotide and yttrium Y 90 edotreotide.